BDBM178100 BRD3308::US11377423, Cmpd 1
SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1ccc(F)cc1N
InChI Key InChIKey=RRJDFENBXIEAPD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 178100
Affinity DataKi: 29nM ΔG°: -10.3kcal/mole IC50: 64nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant human full length HDAC3 using FAM-labeled acetylated peptide A as substrate preincubated for 3 hrs followed by substrate ad...More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of human recombinant HDAC3 at 0.5 uM using AMC-K(Ac)GL as substrate incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair